Collip as a graduate student, ca. 1914. (University of Toronto/Wikimedia Commons)
Bickering And Breakthrough
It wasn’t all sunshine and syringes, however: Tensions were brewing among the overworked team, and Collip actually threatened to keep his purification method a secret from Banting, who nearly attacked Collip but was pulled back by Best before any actual violence occurred. Fortunately, they put their squabbles behind them in time to present their breakthrough to the Association of American Physicians to much fanfare on May 3, 1922. Both Banting and Macleod won the 1923 Nobel Prize for Medicine and kindly split their winnings with Best and Collip, as they all worked together as a team.
Quickly, pharmaceutical companies began developing methods to manufacture insulin, as the slaughterhouse approach left a lot to be desired when it came to both quantity and purity. All over the world, people began waking from their diabetic comas, and parents watched as their children, once on the brink of starvation and death, became normal, happy kids. What was once a death sentence became a highly treatable disease in just over three years of grueling labor on part of the Toronto team, and today, patients with diabetes can expect to live full and long lives.